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These approaches include either targeting all -coronaviruses, targeting a subset of these viruses (such as sarbecoviruses), or even targeting a single species with the aim of developing a pan-variant or variant-proof vaccine for SARS-CoV-2 (Table 1)
While RELM seems to have an important role in inflammation and airway remodeling in rodents [212,213,214,215,216,217], and its overexpression seems to protect from development of asthma symptoms in mice [216], the influence of RELM on asthma outcomes is ambiguous [203,218]
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doi: 10.3233/BMR-170983
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